MEDICO MARKETING OF TOP PCD PHARM FRENCHISE OF BIOETHICS LIFESCIENCS PVT Ltd IN Nausea & Vomiting :-
Nausea :- from the Latin word nausea very unpleasant sensation that one may soon vomit.
Vomiting:- it is the involuntary contractions of the abdominal, thoracic and GI muscles leading to forceful expulsion of stomach contents from the mouth.
How is vomiting reflex stimulated:-
The vomiting reflex is triggered by stimulation of Chemoreceptors in the upper GI track and Mechanoreceptors in the wall of the GI tract which are activated by both contraction and distension of the gut as well as by physical damage.
A coordination center in the central nervous system controls the emetic response.
Afferent nerves to the vomiting center arise from abdominal splanchnic and vagal nerves, the cerebral cortex and the chemoreceptor trigger zone.
Common etiologies of Nausea and vomiting :-
GI Tract disorders – toxins, infections, obstruction, inflammation etc
Pregnancy- During Pregnancy it occurs
Nausea vomiting in pregnancy
Nvp is most common medical condition in pregnancy
This common symptom occurs in approximately 80% of pregnancies and is most marked at gestational week 2-12 .
It is usually most severe in the morning but can occur at any time and increases by cooking odors and strong sharp smells.
Most commonly used medication to prevent Nausea and vomiting:-
Doxinate ( Doxylamine Succinate ) of Svizera Healthacre MUMBAI
Ondem ( Ondensetron 4 mg ) ALKEM
Nilvom Md ( Ondensetron 4 mg ) of TOP PCD PHARM FRENCHISE Bioethics Lifesciences Pvt LTD AMBALA
Pregnidoxin from ucb pharma
Nosic from Indico labs MUMBAI
Luinate from Lupin Laboratories Ltd
Sinate from Serum internation
Sysfol from systopic Labs Ltd
Mode of action of Doxinate :-
it stimulate the Neurotransmitters Dopamine,Histamine and serotonin thereby activation the vomiting centre which causes nausea and vomiting .
DixylAMINE Succinate in Doxinate effectively blocks the chemo receptor trigger zone thereby inhibiting the binding of neurotransmitters and controls nausea.
Pyridoxine Hydrochloride ind Doxinate acts on GI track and eliminates any GI track problem and alleviates morning sickness.
Mode of acting of ONDEM ( alkem) /Nilvom MD of TOP PCD PHARMA FRENCHISE Bioetthics Lifesciences Pvt LTD AMBALA:-
Ondensetron antagonizes 5 HT3 receptor blocking the action of serotonin Nilvom Md is a category B drug and having good results in NVP In Pregnancy and is specifically categorized for NVP associated with chemotherapy/ radiotherapy and nausea caused due to surgery.
Mr. Ravinder Tomar
MD Of Top PCD PHARMA FRENCHISE (BIOETHICS LIFESCIENCES PVT LTD OF AMBALA)